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Browsing by Author "Tukulula, M"

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Curdlan-conjugated PLGA nanoparticles possess macrophage stimulant activity and drug delivery capabilities

Author: Tukulula, M ; Hayeshi, R ; Fonteh, P ; Meyer, D ; Ndamase, A ; Madziva, MT ; Khumalo, V ; Lubuschagne, P ; Naicker, B ; Swai, H ; Dube, A Date: Feb 2015 There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating polymer) could be conjugated to PLGA and nanoparticles from this copolymer would ... Read more
Functionalization of PLGA Nanoparticles with 1,3-ß-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages

Author: Tukulula, M ; Gouveia, L ; Paixao, P ; Hayeshi, R ; Naicker, Brendon ; Dube, A Date: Jun 2018 Mycobacterium tuberculosis which causes tuberculosis, is primarily resident within macrophages. 1,3-ß-glucan has been proposed as a ligand to target drug loaded nanoparticles (NPs) to macrophages. In this study we characterized the intracellular ... Read more
Synthesis, characterization and optimization of poly(p-phenylenediamine)-based organoclay composite for Cr(VI) remediation

Author: Mdlalose, L ; Balogun, Mohammed O ; Setshedi, K ; Tukulula, M ; Chimuka, L ; Chetty, A Date: Apr 2017 The contamination of the water supply with high levels of heavy metals from various human and industrial activities continues to present a major environmental problem. Heavy metals such as hexavalent chromium (Cr(VI)) are of particular concern ... Read more

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Browsing by Author "Tukulula, M"

Browsing by Author "Tukulula, M"

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