How does the non-coding portion of the genome contribute to the regulation of genome architecture? A recent paper by Tan et al. focuses on the relationship between cis-acting complex-trait-associated lincRNAs and the formation of chromosomal contacts in topologically associating domains (TADs).
Reference:
Fanucchi, S. and Mhlanga, M.M. 2017. Enhancer-derived lncRNAs regulate genome architecture: fact or fiction? Trends in Genetics, vol. 33(6): 375-377
Fanucchi, S., & Mhlanga, M. (2017). Enhancer-derived lncRNAs regulate genome architecture: fact or fiction?. http://hdl.handle.net/10204/9940
Fanucchi, Stephanie, and Musa Mhlanga "Enhancer-derived lncRNAs regulate genome architecture: fact or fiction?." (2017) http://hdl.handle.net/10204/9940
Fanucchi S, Mhlanga M. Enhancer-derived lncRNAs regulate genome architecture: fact or fiction?. 2017; http://hdl.handle.net/10204/9940.
Copyright: 2017 Elsevier. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, please consult the publisher's website.