The relationship between mucin (MUC) and pectin (PEC) was explored in an attempt to understand the biomacro-molecular interactions that occur at mucosal surfaces when mucus membranes are exposed to PEC-based materials. These interactions were explored through techniques, such as attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, SEM imagery of lyophilized MUC–PEC blends, thermodynamic analysis, rheology investigations, and in silico static lattice atomistic simulations using a molecular mechanics energy relationships (MMER) approach.
Reference:
Mashingaidze, F, Choonara, Y.E, Kumar, P, du Toit L.C, Maharaj, V, Buchmann, E, Ndesendo, V.M.K and Pillay, V. 2013. Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. Journal of Biomedical Materials Research Part A, pp 1-14
Mashingaidze, F., Choonara, Y., Kumar, P., Du Toit, L., Maharaj, V., Buchmann, E., ... Pillay, V. (2013). Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. http://hdl.handle.net/10204/6966
Mashingaidze, F, YE Choonara, P Kumar, LC Du Toit, V Maharaj, E Buchmann, VMK Ndesendo, and V Pillay "Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface." (2013) http://hdl.handle.net/10204/6966
Mashingaidze F, Choonara Y, Kumar P, Du Toit L, Maharaj V, Buchmann E, et al. Exploration of the biomacromolecular interactions of an interpenetrating proteo-saccharide hydrogel network at the mucosal interface. 2013; http://hdl.handle.net/10204/6966.
Copyright: 2013 Wiley-Blackwell This is an ABSTRACT ONLY. The definitive version is published in Journal of Biomedical Materials Research Part A, pp 1-14
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