A polymer system (polyvinylpyrrolidone + polyvinyl acetate-co-crotonic acid) was successfully identified for use as encapsulation material for sensitive actives using supercritical CO2 as plasticisation medium, having the following properties: 1. Ability to plasticise sufficiently in supercritical CO2, 2. Ability to form an inter-polymer complex in supercritical CO2, 3. Ability to swell in aqueous medium in order to release actives, and 4. FDA-approved.
Reference:
Labuschagne, P.W. 2004. Plasticisation and complexation of certain polymers in supercritical co2. Master thesis. The Tshwane University of Technology, Faculty of Engineering Department of polymer technology
Labuschagne, P. W. (2004). Plasticisation and complexation of certain polymers in supercritical CO2 (Workflow;9671). Research Gate. Retrieved from http://hdl.handle.net/10204/6667
Labuschagne, Philip W Plasticisation and complexation of certain polymers in supercritical CO2. Workflow;9671. Research Gate, 2004. http://hdl.handle.net/10204/6667
Labuschagne PW. Plasticisation and complexation of certain polymers in supercritical CO2. 2004 [cited yyyy month dd]. Available from: http://hdl.handle.net/10204/6667
A thesis submitted to Faculty of engineering
Department of polymer technology, Tshwane University of Technology, in fulfillment of the requirements for Master of Technology.