A variety of strategies have been utilised for prevention and treatment of chronic wounds such as leg ulcers, diabetic foot ulcers and pressure sores. Low Level Laser Therapy (LLLT) has been reported to be an invaluable tool in the enhancement of wound healing through stimulating cell proliferation, accelerating collagen synthesis and increasing ATP synthesis in mitochondria to name but a few. This study focused on an in-vitro analysis of the cellular responses induced by treatment with three different laser beam profiles. The promoted cellular alterations were measured by increase in cell viability, cell proliferation and cytotoxicity. The results obtained showed that when cells undergo laser irradiation some cellular processes are driven by the peak energy density rather than the energy of the laser beam
Reference:
Mthunzi, P, Forbes, A, Hawkins, D. 2006.Influence of laser beam shape on in-vitro cellular and molecular transformations in human skin fibroblasts. 51st Annual Conference of the SAIP, University of the Western Cape, South Africa, 3-7 July 2006, pp 1
Mthunzi, P., Forbes, A., Hawkins, D., Abrahamse, H., & Karsten, A. (2006). Influence of laser beam shape on in-vitro cellular and molecular transformations in human skin fibroblasts. http://hdl.handle.net/10204/2990
Mthunzi, P, A Forbes, D Hawkins, H Abrahamse, and AE Karsten. "Influence of laser beam shape on in-vitro cellular and molecular transformations in human skin fibroblasts." (2006): http://hdl.handle.net/10204/2990
Mthunzi P, Forbes A, Hawkins D, Abrahamse H, Karsten A, Influence of laser beam shape on in-vitro cellular and molecular transformations in human skin fibroblasts; 2006. http://hdl.handle.net/10204/2990 .
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