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New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers

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dc.contributor.author Rotherham, L
dc.contributor.author Gresh, L
dc.contributor.author Ngubane, N
dc.contributor.author Nhlapo, J
dc.contributor.author Khati, M
dc.date.accessioned 2008-12-10T12:39:25Z
dc.date.available 2008-12-10T12:39:25Z
dc.date.issued 2008-11
dc.identifier.citation Rotherham, L, Gresh, L, Ngubane, N et al. 2008. New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers. Science real and relevant: 2nd CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 17 & 18 November 2008, pp 1 en
dc.identifier.uri http://hdl.handle.net/10204/2700
dc.description Science Real and Relevant: 2nd CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 17 & 18 November 2008 en
dc.description.abstract The CSIR bioscientists are using aptamers to explore new strategies for diagnosis and mitigation of the virulence of TB. The scientists have expressed and purified His-tagged versions of TB secreted proteins ESAT-6 and CFP-10. These monomers were to form the heterodimer in vitro. The scientists test the ability of the apmaters to: 1) be used as TB diagnostics tools by detecting the presence of ESAT-6 and/or CFP-10 in blood or sputum samples; 2) inhibit the virulence of M. tuberculosis in vitro and in TB mouse models. en
dc.language.iso en en
dc.publisher CSIR en
dc.subject Tuberculosis en
dc.subject Aptamers en
dc.title New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers en
dc.type Conference Presentation en
dc.identifier.apacitation Rotherham, L., Gresh, L., Ngubane, N., Nhlapo, J., & Khati, M. (2008). New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers. CSIR. http://hdl.handle.net/10204/2700 en_ZA
dc.identifier.chicagocitation Rotherham, L, L Gresh, N Ngubane, J Nhlapo, and M Khati. "New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers." (2008): http://hdl.handle.net/10204/2700 en_ZA
dc.identifier.vancouvercitation Rotherham L, Gresh L, Ngubane N, Nhlapo J, Khati M, New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers; CSIR; 2008. http://hdl.handle.net/10204/2700 . en_ZA
dc.identifier.ris TY - Conference Presentation AU - Rotherham, L AU - Gresh, L AU - Ngubane, N AU - Nhlapo, J AU - Khati, M AB - The CSIR bioscientists are using aptamers to explore new strategies for diagnosis and mitigation of the virulence of TB. The scientists have expressed and purified His-tagged versions of TB secreted proteins ESAT-6 and CFP-10. These monomers were to form the heterodimer in vitro. The scientists test the ability of the apmaters to: 1) be used as TB diagnostics tools by detecting the presence of ESAT-6 and/or CFP-10 in blood or sputum samples; 2) inhibit the virulence of M. tuberculosis in vitro and in TB mouse models. DA - 2008-11 DB - ResearchSpace DP - CSIR KW - Tuberculosis KW - Aptamers LK - https://researchspace.csir.co.za PY - 2008 T1 - New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers TI - New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers UR - http://hdl.handle.net/10204/2700 ER - en_ZA


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