The South African gold mining industry recently joined the World Health Organisation Global Campaign to Eliminate Silicosis. Subsequently, a number of research projects are being focused on the evaluation of silica dust levels and dust allaying measures. The objectives of the project were to: Undertake a comprehensive literature survey to identify biomarkers for the early detection and / or prediction of silicosis, 2 Develop a systematic framework for the evaluation of studies on biomarkers, 3 Conduct a meta-analysis of data, if appropriate, 4 Hold a workshop of international experts, primarily to evaluate the potential for conducting a Phase II study and 5 Develop an outline of a proposal for a Phase II evaluation of any promising markers(s) identified
Reference:
Murray, J, et al. 2004. Markers for prediction and early detection of Pneumoconiosis. Safety in Mines Research Advisory Committee, SIM 030803, March, 2004, pp 1-63
Murray, J., Gulumian, M., Nelson, G., Darwin, L., Borm, P., Castranova, V., ... Vallyathan, V. (2004). Markers for prediction and early detection of Pneumoconiosis. http://hdl.handle.net/10204/1326
Murray, J, M Gulumian, G Nelson, L Darwin, P Borm, V Castranova, K Donaldson, and V Vallyathan. "Markers for prediction and early detection of Pneumoconiosis." (2004): http://hdl.handle.net/10204/1326
Murray J, Gulumian M, Nelson G, Darwin L, Borm P, Castranova V, et al, Markers for prediction and early detection of Pneumoconiosis; 2004. http://hdl.handle.net/10204/1326 .
