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Browsing by Author "Savulescu, AF"

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Biochemical pulldown of mRNAs and long noncoding RNAs from cellular lysates coupled with mass spectrometry to identify protein binding partners

Author: Savulescu, AF ; Stoychev, Stoyan H ; Mamputha, Sipho ; Mhlanga, MM Date: Jun 2020 RNA binding proteins (RBPs) interact with cellular mRNAs, controlling various steps throughout the lifetime of these transcripts, including transcription, cellular transport, subcellular localization, translation and degradation. In addition ... Read more
Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti

Author: Scholefield, Janine ; Henriques, R ; Savulescu, AF ; Fontan, E ; Boucharlat, A ; Laplantine, E ; Smahi, A ; Israel, A ; Agou, F ; Mhlanga, Musa Date: Sep 2016 The NF- B pathway has critical roles in cancer, immunity and inflammatory responses. Understanding the mechanism(s) by which mutations in genes involved in the pathway cause disease has provided valuable insight into its regulation, yet many ... Read more

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Browsing by Author "Savulescu, AF"

Browsing by Author "Savulescu, AF"

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