Author:Kenyon, CP; Steyn, A; Roth, Robyn L; Steenkamp, PA; Nkosi, TC; Oldfield, LCDate:Jul 2011Kinase and synthetase enzymes utilise C8D-ATP in preference to non-deuterated ATP. The KIE obtained at low ATP concentrations is clearly a primary KIE demonstrating strong evidence that the bond to the isotopically substituted hydrogen is ...Read more