Author:Magagula, L; Gagliardi, M; Naidoo, Jerolen; Mhlanga, MusaDate:Aug 2017Termed 'master gene regulators' long ncRNAs (lncRNAs) have emerged as the true vanguard of the 'noncoding revolution'. Functioning at a molecular level, in most if not all cellular processes, lncRNAs exert their effects systemically. Thus, ...Read more
Author:Shibayama, Y; Fanucchi, Stephanie; Magagula, L; Mhlanga, MusaDate:May 2014Recent functional studies have unveiled the significant role chromatin topology plays in gene regulation. Several lines of evidence suggest genes access necessary factors for transcription by forming chromatin loops. A clearer picture of the ...Read more