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Browsing by Author "De Mieri, M"

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Antitrypanosomal isoflavan quinones from Abrus precatorius

Author: Hata, Y ; Ebrahimi, SN ; De Mieri, M ; Zimmermann, S ; Mokoka, T ; Naidoo, Dashnie ; Fouché, Gerda ; Maharaj ; Kaiser, M ; Brun, R ; Potterat, O ; Hamburger, M Date: Mar 2014 Human African trypanosomiasis is a neglected tropical disease in sub Saharan Africa that is fatal if left untreated. In a search for new natural products with antitrypanosomal activity, we recently identified abruquinones B and I from Abrus ... Read more
Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products

Author: Zimmermann, S ; Fouché, Gerda ; De Mieri, M ; Yukiko, Y ; Toyonobu ; Nthambeleni, R ; Parkinson, CJ ; Van der Westhuyzen, Christiaan W ; Kaiser, M ; Hamburger, M ; Adams, M Date: Mar 2014 Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis. To explore their structure-antitrypanosomal ... Read more
Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products

Author: Zimmermann, S ; Fouché, Gerda ; De Mieri, M ; Yukiko, Y ; Toyonobu, U ; Nthambeleni, R ; Parkinson, CJ ; Van der Westhuyzen, Christiaan W ; Kaiser, M ; Hamburger, M ; Adams, M Date: Mar 2014 Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis. To explore their structure-antitrypanosomal ... Read more

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Browsing by Author "De Mieri, M"

Browsing by Author "De Mieri, M"

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