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Browsing by Author "Chouteau, F"

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Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore

Author: Pillay, P ; Vleggaar, R ; Maharaj, VJ ; Smith, PJ ; Lategan, CA ; Chouteau, F ; Chibale, K Date: Feb 2007 The dichloromethane extract of the leaves of Vernonia staehelinoides Harv. (Asteraceae) showed in vitro activity (IC50 ~3 µg/ml) against the chloroquine-sensitive (D10) and the chloroquine-resistant (K1) strains of Plasmodium falciparum. ... Read more
Design, synthesis, and in vitro antituberculosis activity of 2(5H)-Furanone derivatives

Author: Ngwane, AH ; Panayides, Jenny-Lee ; Chouteau, F ; Macingwana, L ; Viljoen, A ; Baker, B ; Madikane, E ; De Kock, C ; Wiesner, L ; Chibale, K ; Parkinson, CJ ; Mmutlane, EM ; Van Helden, P ; Wiid, I Date: Jan 2016 A series of 2(5H)-furanone-based compounds were synthesized from commercially available mucohalic acids. From the first-generation compounds, three showed inhibitory activity (10 µg/mL) of at least 35% against Mycobacterium smegmatis mc(2) ... Read more

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Browsing by Author "Chouteau, F"

Browsing by Author "Chouteau, F"

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