Author:Thimiri Govindaraj, Deepak BDate:Sep 2023Background: The Global Biofoundry Alliance (GBA) has been established between countries including the UK, US, Japan, Singapore, China, Australia, Denmark, and Canada through 16 research institutions. GBA plays a key role in the synthetic ...Read more
Author:Baichan, P; Naicker, Previn; Devar, J; Smith, M; Nweke, EEDate:Jan 2023Gallbladder cancer (GBC) is the most frequent biliary tract cancer (including cancers of the intra- and extrahepatic biliary tree). Like many biliary tract carcinomas, GBC is identified by late diagnosis, poor prognosis, and ineffective ...Read more
Author:Latha, S; Selvamani, P; Palanisamy, SB; Thimiri Govindaraj, Deepak B; Thangavelu, PDate:Nov 2021The magnetic nanoparticles are said to be a class of nanoparticles or nanomaterials that can be manipulated by the help of externally applied magnetic field. These magnetic nanoparticles constitute materials such as nickel, cobalt, iron, and ...Read more
Author:Mathekga, BSP; Nxumalo, Precious Z; Thimiri Govindaraj, Deepak BDate:Jan 2022In this book chapter, we elaborate on the state-of-the-art technology developments in high throughput screening, microfluidics and nanofluidics. This book chapter further elaborated on the application of microfluidics and nanofluidics for ...Read more
Author:Dube, A; Semete-Makokotlela, Boitumelo; Ramalapa, Bathabile E; Reynolds, J; Boury, FDate:Mar 2021The increasing prevalence of drug resistant pathogenic strains, including multi drug resistant TB along with the growing HIV and malaria resistance demand new routes of innovation for pharmaceutical drug discovery. Nanomedicine provides the ...Read more
Author:Grobler, Lichelle R; Suleman, Essa; Thimiri Govindaraj, Deepak BDate:Feb 2021CRISPR technology has revolutionized biological research in the last decade and many academic institutions and companies have patented CRISPR systems and applications. Several patents have been filed for various applications of CRISPR in ...Read more
Author:Nxumalo, Precious Z; Takundwa, MM; Thimiri Govindaraj, Deepak BDate:Feb 2021In this review chapter, we provide full comprehensive analysis on the patent, ethics and biosafety regulation with respect to the application of CRISPR technology in mammalian systems. We focused on recent development in CRISPR technology and ...Read more
Author:Latha, S; Palanisamy, S; Chakrapani, P; Harinia, R; Babu, PS; Thimiri Govindaraj, Deepak BDate:Mar 2021Background: Drug delivery is a science that requires the development of tailored systems that can deliver defi nedquantities of a therapeutic payload at a specifi c target site, at a controlled release rate, with or without a specifi c ...Read more
Author:Batohi, Nikayla; Dreyer, G; Thimiri Govindaraj, Deepak BDate:Jan 2023More than half of the women diagnosed with ovarian cancer ultimately succumb to death after 5 years of diagnosis. Standard platinum-based chemotherapy often results in patient relapse; thus, new therapeutic strategies are required. We aim to ...Read more
Author:Latha, S; Selvamani, P; Suganya, G; Thimiri Govindaraj, Deepak B; Pal, TKDate:Jun 2021Magnetic microspheres incorporated with pantoprazole sodium—a proton pump inhibitor—were formulated by using two different polymers such as ethyl cellulose and Eudragit RS-100. The magnetic microspheres were prepared by emulsion solvent ...Read more
Author:Smith, Tanya; O’Kennedy, Martha M; Ross, CS; Lewis, NS; Abolnik, CDate:Feb 2023Newcastle disease (ND) is a highly contagious viral respiratory and neurological disease that has a severe impact on poultry production worldwide. In the present study, an expression platform was established for the transient production in ...Read more
Author:Baichan, P; Naicker, Previn; Augustine, TN; Smith, M; Candy, G; Devar, J; Nweke, EEDate:Mar 2023Background Gallbladder cancer (GBC) is a lethal cancer with a poor prognosis. The lack of specifc and sensitive biomarkers results in delayed diagnosis with most patients presenting at late stages of the disease. Furthermore, there is little ...Read more