Author:Sari-Ak, D; Alomari, O; Shomali, RA; Lim, J; Thimiri Govindaraj, Deepak BDate:Dec 2022The baculovirus expression vector systems (BEVS) have been widely used for the recombinant production of proteins in insect cells and with high insert capacity. However, baculovirus does not replicate in mammalian cells; thus, the BacMam ...Read more
Author:Kenmogne, Vanelle L; Nweke, EE; Takundwa, Mutsa M; Fru, PN; Thimiri Govindaraj, Deepak BDate:Oct 2022Drug resistance in leukaemia is a major problem that needs to be addressed. Precision medicine provides an avenue to reduce drug resistance through a personalised treatment plan. It has helped to better stratify patients based on their molecular ...Read more
Author:Nweke, EE; Suleman, Essa; Du Plessis, M; Thimiri Govindaraj, Deepak BDate:Aug 2021In this book chapter, we focus on application of genome annotation and analysis of microbes for synthetic biology and cancer biology research. We particularly emphasised on application of microbial genomics in synthetic biology and cancer ...Read more
Author:Thimiri Govindaraj, Deepak BDate:Jan 2022Global bio-foundry Alliance (GBA) has been established between countries including the UK, US, Japan, Singapore, China, Australia, Denmark, and Canada through 16 research institutions. Global bio-foundry Alliance plays the key role in the ...Read more
Author:Thimiri Govindaraj, Deepak BDate:Mar 2023Background: Global bio-foundry Alliance (GBA) has been established between countries including the UK, US, Japan, Singapore, China, Australia, Denmark, and Canada through 16 research institutions. Global bio-foundry Alliance plays the key ...Read more
Author:Thimiri Govindaraj, Deepak B; Nxumalo, Precious ZDate:Feb 2021Dr. Deepak Balaji Thimiri Govindaraj has been selected for an e-Poster presentation at the 2nd ESH Translational Research Conference on Chronic Lymphocytic Leukaemia. The Conference is proposing a programme of leading-edge basic and clinical ...Read more
Author:Nweke, EE; Thimiri Govindaraj, Deepak BDate:Feb 2021In this chapter, we delineated the methods of CRISPR technology that has been used for the development of engineered insect cell line. We elaborated on how CRISPR/Cas9 genome editing in Drosophila melanogaster, Bombyx mori, Spodoptera frugiperda ...Read more
Author:Nweke, EE; Thimiri Govindaraj, Deepak BDate:Feb 2021One of the critical Global challenges in achieving the UN Sustainable Development Goals 3 Good Health and Well Being is optimizing drug discovery and translational research for unmet medical need in both communicable and non-communicable ...Read more
Author:Thimiri Govindaraj, Deepak BDate:Sep 2023Background: The Global Biofoundry Alliance (GBA) has been established between countries including the UK, US, Japan, Singapore, China, Australia, Denmark, and Canada through 16 research institutions. GBA plays a key role in the synthetic ...Read more
Author:Latha, S; Selvamani, P; Palanisamy, SB; Thimiri Govindaraj, Deepak B; Thangavelu, PDate:Nov 2021The magnetic nanoparticles are said to be a class of nanoparticles or nanomaterials that can be manipulated by the help of externally applied magnetic field. These magnetic nanoparticles constitute materials such as nickel, cobalt, iron, and ...Read more
Author:Mathekga, BSP; Nxumalo, Precious Z; Thimiri Govindaraj, Deepak BDate:Jan 2022In this book chapter, we elaborate on the state-of-the-art technology developments in high throughput screening, microfluidics and nanofluidics. This book chapter further elaborated on the application of microfluidics and nanofluidics for ...Read more
Author:Grobler, Lichelle R; Suleman, Essa; Thimiri Govindaraj, Deepak BDate:Feb 2021CRISPR technology has revolutionized biological research in the last decade and many academic institutions and companies have patented CRISPR systems and applications. Several patents have been filed for various applications of CRISPR in ...Read more
Author:Nxumalo, Precious Z; Takundwa, MM; Thimiri Govindaraj, Deepak BDate:Feb 2021In this review chapter, we provide full comprehensive analysis on the patent, ethics and biosafety regulation with respect to the application of CRISPR technology in mammalian systems. We focused on recent development in CRISPR technology and ...Read more
Author:Latha, S; Palanisamy, S; Chakrapani, P; Harinia, R; Babu, PS; Thimiri Govindaraj, Deepak BDate:Mar 2021Background: Drug delivery is a science that requires the development of tailored systems that can deliver defi nedquantities of a therapeutic payload at a specifi c target site, at a controlled release rate, with or without a specifi c ...Read more
Author:Batohi, Nikayla; Dreyer, G; Thimiri Govindaraj, Deepak BDate:Jan 2023More than half of the women diagnosed with ovarian cancer ultimately succumb to death after 5 years of diagnosis. Standard platinum-based chemotherapy often results in patient relapse; thus, new therapeutic strategies are required. We aim to ...Read more
Author:Latha, S; Selvamani, P; Suganya, G; Thimiri Govindaraj, Deepak B; Pal, TKDate:Jun 2021Magnetic microspheres incorporated with pantoprazole sodium—a proton pump inhibitor—were formulated by using two different polymers such as ethyl cellulose and Eudragit RS-100. The magnetic microspheres were prepared by emulsion solvent ...Read more